膜粘连蛋白A1抗体
规格：1mg/1ml
英文名： Annexin A1
别名： Annexin A1; Annexin I; AnnexinA1; AnnexinI; ANX 1; ANX A1; ANX1; ANXA 1; ANXA1; ANXA1 protein; Calpactin II; CalpactinII; Chromobindin 9; Chromobindin9; HGNC:533; Lipocortin 1; Lipocortin I; Lipocorti
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Annexin
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆 细胞膜
膜粘连蛋白A1抗体产品介绍：background: This gene encodes a protein that belongs to a family of Ca(2+) dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti inflammatory activity. Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. 膜粘连蛋白A1抗体This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Subunit: Homodimer in placenta (20%); linked by transglutamylation. Interacts with DYSF (By similarity). Subcellular Location: Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages. Post-translational modifications: Phosphorylated by膜粘连蛋白A1抗体 protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity. Similarity: Belongs to the annexin family. Contains 4 annexin repeats. Gene ID: 301 Database links: Entrez Gene: 301 Human Entrez Gene: 16952 Mouse Entrez Gene: 25380 Rat Omim: 151690 Human SwissProt: P04083 Human SwissProt: P10107 Mouse SwissProt: P07150 Rat Unigene: 494173 Human Unigene: 248360 Mouse Unigene: 1792 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜粘连蛋白A1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid