胎盘特异基因8蛋白抗体
规格：1mg/1ml
英文名： PLAC8
别名： C15; Onzin; PLAC8; PLAC8_HUMAN; Placenta specific 8; Placenta-specific gene 8 protein; Protein C15.
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PLAC8
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：
胎盘特异基因8蛋白抗体产品介绍：background: PLAC8 is a 115 amino acid protein belonging to the cornifelin family that is expressed at high levels in plasmacytoid dendritic cells and other organs of the immune system including lymph nodes, spleen, bone marrow and peripheral blood leukocytes, with lower expression in appendix, thymus and fetal liver. Human PLAC8 shares 83% homology with murine PLAC8, where it has been identified in placenta from 9.5-18.5 days postcoitum. The gene encoding PLAC8 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded 胎盘特异基因8蛋白抗体glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied 胎盘特异基因8蛋白抗体to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease Function: Subunit: Tissue Specificity: Expressed at high levels in plasmacytoid dendritic cells. High expression in spleen, lymph nodes, peripheral blood leukocytes, and bone marrow, with lower expression in thymus, appendix, and fetal liver. Post-translational modifications: DISEASE: Similarity: Database links: Entrez Gene: 51316 Human Omim: 607515 Human SwissProt: Q9NZF1 Human Unigene: 546392 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet 胎盘特异基因8蛋白抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid