胰岛素样生长因子结合蛋白样1抗体
规格：1mg/1ml
英文名： IGFBPL1
别名： bA113O24.1; IGFBP-related protein 10; IGFBP-RP4; IGFBPRP4; insulin-like growth factor binding protein related protein 4; insulin-like growth factor-binding protein-like 1; IBPL1_HUMAN; insulin-like gr
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGFBPL1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：分泌型蛋白
胰岛素样生长因子结合蛋白样1抗体产品介绍：background: IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is 胰岛素样生长因子结合蛋白样1抗体found at lower levels in the prostate, bladder and lung. Function: IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of 胰岛素样生长因子结合蛋白样1抗体IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein. Subcellular Location: Secreted. Tissue Specificity: Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 Kazal-like domain. Database links: UniProtKB/Swiss-Prot: Q8WX77.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素样生长因子结合蛋白样1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid