细胞纤毛内转运同源蛋白81抗体
规格:1mg/1ml
英文名: IFT81
别名: Carnitine deficiency associated expressed in ventricle 1 isoform 2; Carnitine deficiency-associated protein expressed in ventricle 1; CDV-1; CDV1; CDV1R; Ift81; IFT81_HUMAN; intraflagellar transport 8
分子量: 80kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IFT81
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
细胞纤毛内转运同源蛋白81抗体产品介绍:background: IFT81 is a 676 amino acid protein that is present at high levels in testis and is moderately expressed in heart, liver, ovary, pancreas, kidney and skeletal muscle. Existing as three alternatively spliced isoforms, two of which are designated CDV-1 and CDV-1R, IFT81 plays a role in testicular development and spermatogenesis and may also be involved in cardiac hypertrophy caused by carnitine deficiency. The gene encoding IFT81 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.细胞纤毛内转运同源蛋白81抗体 Function: Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity). Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity). Tissue Specificity: Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected细胞纤毛内转运同源蛋白81抗体 in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. Database links: Entrez Gene: 28981 Human SwissProt: Q8WYA0 Human Unigene: 528382 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞纤毛内转运同源蛋白81抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid