细胞纤毛内转运同源蛋白20抗体
规格:1mg/1ml
英文名: IFT20
别名: hIFT20; Intraflagellar transport 20 homolog (Chlamydomonas); Intraflagellar transport protein 20 like; IFT20_HUMAN; Intraflagellar transport protein IFT20.
分子量: 15kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IFT20
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
细胞纤毛内转运同源蛋白20抗体产品介绍:background: IFT20 is a gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14. Function: Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a 细胞纤毛内转运同源蛋白20抗体role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Subunit: Component of IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20. Interacts directly with IFT57 and KIF3B/Kinesin II subunit (By similarity). Interacts with CCDC41/CEP83. Subcellular Location: Golgi apparatus, cis-Golgi network (By similarity). Cytoplasm, 细胞纤毛内转运同源蛋白20抗体cytoskeleton, centrosome, centriole (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By similarity). Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole. Associated with basal body at the base of primary cilia (By similarity). Tissue Specificity: Expressed in almost all tissues. Database links: UniProtKB/Swiss-Prot: Q8IY31.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞纤毛内转运同源蛋白20抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid