160kDa内含子结合蛋白抗体
规格:1mg/1ml
英文名: IBP160
别名: AQR; AQR_HUMAN; aquarius; aquarius homolog (mouse); DKFZp686B23123; fSAP164; functional spliceosome-associated protein 164; IBP160; Intron-binding protein aquarius; Intron-binding protein of 160 kDa;
分子量: 171kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IBP160
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
160kDa内含子结合蛋白抗体产品介绍:background: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) 160kDa内含子结合蛋白抗体during the late stages of splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm. Similarity: Belongs to the CWF11 family. Database links: Entrez Gene: 9716 Human160kDa内含子结合蛋白抗体 Omim: 610548 Human SwissProt: O60306 Human Unigene: 510958 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
160kDa内含子结合蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid