干扰素诱导的三角形四肽重复蛋白2抗体
规格：1mg/1ml
英文名： IFIT2
别名： CIG-42; cig42; G10P2; GARG 39; Glucocorticoid attenuated response gene 39; IFI 54; P54; IFI 54K; IFI-54K; IFI54; IFIT 2; IFIT-2; IFIT2; IFIT2_HUMAN; Interferon induced 54 kDa protein; Interferon induc
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IFIT2
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：
干扰素诱导的三角形四肽重复蛋白2抗体产品介绍：Function: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. Subunit: Domain-swapped homodimer.干扰素诱导的三角形四肽重复蛋白2抗体 Component of an interferon-dependent multiprotein complex, at least composed of IFIT1, IFIT2 and IFIT3. Interacts with IFIT1 and IFIT3. Interacts with TMEM173/MITA and disrupts its interaction with MAVS or TBK1. Interacts with干扰素诱导的三角形四肽重复蛋白2抗体 EIF3E and EIF3C. Subcellular Location: Cytoplasm. Endoplasmic reticulum. Similarity: Belongs to the IFIT family. Contains 9 TPR repeats. Gene ID: 3433 Database links: Entrez Gene: 3433 Human Omim: 147040 Human SwissProt: P09913 Human Unigene: 437609 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
干扰素诱导的三角形四肽重复蛋白2抗体研究领域：细胞生物 **学 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid