真核翻译起始因子3亚基L/eIF3e蛋白抗体
规格：1mg/1ml
英文名： IF3EI
别名： eIEF associated protein HSPC021; EIF3EIP; eIF3l; eif3l; EIF3L_HUMAN; EIF3S11; EIF3S6IP; Eukaryotic translation initiation factor 3 subunit 6 interacting; Eukaryotic translation initiation factor 3 sub
分子量： 67kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IF3EI
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
真核翻译起始因子3亚基L/eIF3e蛋白抗体产品介绍：Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Subunit: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B,真核翻译起始因子3亚基L/eIF3e蛋白抗体 EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to 真核翻译起始因子3亚基L/eIF3e蛋白抗体phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3 (By similarity). Subcellular Location: Cytoplasm. Similarity: Belongs to the eIF-3 subunit L family. Gene ID: 51386 Database links: Entrez Gene: 51386 Human Entrez Gene: 223691 Mouse SwissProt: Q9Y262 Human SwissProt: Q8QZY1 Mouse Unigene: 446852 Human Unigene: 206404 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
真核翻译起始因子3亚基L/eIF3e蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid