胃蛋白酶原C抗体
规格：1mg/1ml
英文名： Pepsinogen II
别名： PG-C; Pepsinogen C; Progastricsin; Pepsinogen II; Pepsinogen-2; Pepsinogen2; PEPC_HUMAN; Gastricsin; Pepsinogen C; PEPC; pepsin C; pepsinogen group II; PGC; PGII; preprogastricsin.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PG-C
交叉反应：Human, Mouse, Rat, Chicken, Cow,
细胞定位：分泌型蛋白
胃蛋白酶原C抗体产品介绍：background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases 胃蛋白酶原C抗体including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq]. Function: Hydrolyzes a variety of proteins. Subcellular Location: Secreted. Similarity: Belongs to 胃蛋白酶原C抗体the peptidase A1 family. Gene ID: 5225 Database links: Entrez Gene: 5225 Human Entrez Gene: 24864 Rat Omim: 169740 Human SwissProt: P20142 Human SwissProt: P04073 Rat Unigene: 1867 Human Unigene: 9735 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胃蛋白酶原C(PG-C)主要用于胃癌及其癌前病变易感性的关系。
胃蛋白酶原C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit