乙醛脱氢酶家族3成员A1抗体
规格:1mg/1ml
英文名: ALDH3A1
别名: AHD 4; AHD C; Ahd4; AHDC; AL3A1_HUMAN; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase 3 family member A1; Aldehyde dehydrogenase 3 family, member A1; Aldehyde dehydrogenase 3A1; Aldehyde dehydrogena
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ALDH3A1
交叉反应:Human, Mouse, Rat, Pig, Horse,
细胞定位:
乙醛脱氢酶家族3成员A1抗体产品介绍:background: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]. Function: ALDHs play a major role in the乙醛脱氢酶家族3成员A1抗体 detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. Subunit: Homodimer. Subcellular Location: Cytoplasm. Tissue Specificity: High levels in stomach, esophagus and lung; low level in乙醛脱氢酶家族3成员A1抗体 the liver and kidney. Similarity: Belongs to the aldehyde dehydrogenase family. Database links: Entrez Gene: 218 Human Entrez Gene: 11670 Mouse Entrez Gene: 25375 Rat Omim: 100660 Human SwissProt: P30838 Human SwissProt: P47739 Mouse SwissProt: P11883 Rat Unigene: 531682 Human Unigene: 4257 Mouse Unigene: 105627 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乙醛脱氢酶家族3成员A1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid