HERPUD蛋白家族成员2抗体
规格:1mg/1ml
英文名: HERPUD2
别名: FLJ22313; FLJ31032; HERP2_HUMAN; HERPUD 2; HERPUD family member 2; HERPUD2; Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 2; Homocysteine responsive endopl
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HERPUD2
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:
HERPUD蛋白家族成员2抗体产品介绍:background: The endoplasmic reticulum (ER) stress response is triggered by the accumulation of unfolded proteins within the ER and is characterized by three events: the inhibition of translation (to prevent further protein accumulation), the up-regulated expression of polypeptide-folding proteins (known as the unfolded protein response or UPR) and the degradation of misfolded proteins by the ER-associated protein degradation (ERAD) system. Members of the homocysteine-inducible and ER stress-inducible ubiquitin-like domain families are components of the ERAD system and, via their ubiquitin-like domain, are thought to be involved in the destruction of misfolded proteins. HERPUD2 (Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2) is aHERPUD蛋白家族成员2抗体 406 amino acid single-pass membrane protein containing one N-terminal ubiquitin-like domain. HERPUD2 is thought to be involved in the unfolded protein response (UPR) pathway. Function: Could be involved in the unfolded protein response (UPR) pathway (By similarity). Subcellular Location: Membrane; Single-pass membrane protein (Potential). Similarity: Contains 1 ubiquitin-like domain. Database links: Entrez HERPUD蛋白家族成员2抗体Gene: 64224 Human Entrez Gene: 80517 Mouse Entrez Gene: 300463 Rat SwissProt: Q9BSE4 Human SwissProt: Q9JJC9 Mouse SwissProt: Q66HH4 Rat Unigene: 643051 Human Unigene: 142843 Mouse Unigene: 231721 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HERPUD蛋白家族成员2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid