PWWP域包含蛋白1抗体
规格:1mg/1ml
英文名: HDGFL1
别名: HDGFL1; HDGL1_HUMAN; Hepatoma-derived growth factor-like protein 1; PWWP domain-containing protein 1; PWWP1.
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HDGFL1
交叉反应:Human,
细胞定位:
PWWP域包含蛋白1抗体产品介绍:background: Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimu-lates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRPPWWP域包含蛋白1抗体 (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specif-ically it is strongly expressed in bulbus, olfactorius, piriform cortex and amygdala complex while HRP-2 in brain is located in the thalamus, prefrontal and parietal cortexPWWP域包含蛋白1抗体 neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins play a role in neuron proliferation and cell survival. Similarity: Belongs to the HDGF family. Contains 1 PWWP domain. Database links: Entrez Gene: 154150 Human SwissProt: Q5TGJ6 Human Unigene: 629246 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PWWP域包含蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid