羊毛甾醇14α-去甲基化酶蛋白抗体
规格：1mg/1ml
英文名： CYP51A1
别名： Lanosterol 14-alpha demethylase; LDM; CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Sterol 14-alpha demethylase; CP51A_HUMAN.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CYP51A1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：
羊毛甾醇14α-去甲基化酶蛋白抗体产品介绍：background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by羊毛甾醇14α-去甲基化酶蛋白抗体 RefSeq, Mar 2009] Function: Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Subcellular Location: Endoplasmic reticulum membrane (Potential). Microsome membrane (Potential). 羊毛甾醇14α-去甲基化酶蛋白抗体Tissue Specificity: Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung. Similarity: Belongs to the cytochrome P450 family. Gene ID: 1595 Database links: Entrez Gene: 1595 Human Omim: 601637 Human SwissProt: Q16850 Human Unigene: 417077 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
羊毛甾醇14α-去甲基化酶蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid