H2B组蛋白家族成员W蛋白抗体
规格：1mg/1ml
英文名： H2BFWT
别名： H2B histone family member W testis-specific; H2BFWT; H2BWT_HUMAN; Histone H2B type W-T.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human H2BFWT
交叉反应：Human,
细胞定位：
H2B组蛋白家族成员W蛋白抗体产品介绍：background: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function. Function: Atypical histone H2B. NucleosomesH2B组蛋白家族成员W蛋白抗体 containing it are structurally and dynamically indistinguishable from those containing conventional H2B. However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes. May be important for telomere function. Subunit: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H2B组蛋白家族成员W蛋白抗体H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Subcellular Location: Nucleus membrane. Chromosome. Tissue Specificity: Testis-specific. Present in sperm cells (at protein level). Similarity: Belongs to the histone H2B family. Database links: UniProtKB/Swiss-Prot: Q7Z2G1.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
H2B组蛋白家族成员W蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 染色质和核信号 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid