肉毒碱O-乙酰基转移酶
规格：1mg/1ml
英文名： CRAT
别名： CACP_HUMAN; Carnitine acetylase; Carnitine acetyltransferase; Carnitine O acetyltransferase; Carnitine O-acetyltransferase; CAT; CAT1; CrAT;
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRAT
交叉反应：Human, Mouse, Rat, Chicken,
细胞定位：
肉毒碱O-乙酰基转移酶产品介绍：background: CRAT is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. Function: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Subunit: Monomer. Subcellular Location: Endoplasmic 肉毒碱O-乙酰基转移酶reticulum (Potential). Peroxisome (Potential). Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (Potential). Isoform 1: Mitochondrion (Potential). Isoform 2: Peroxisome (Potential). Tissue Specificity: Mostly in skeletal muscle, less in肉毒碱O-乙酰基转移酶 heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney. Similarity: Belongs to the carnitine/choline acetyltransferase family. Database links: Entrez Gene: 6541 Human Entrez Gene: 11987 Mouse Omim: 104615 Human SwissProt: P30825 Human SwissProt: Q09143 Mouse Unigene: 14846 Human Unigene: 275489 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肉毒碱O-乙酰基转移酶产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 信号转导 脂蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid