G蛋白偶联受体GPRC5C蛋白抗体
规格：1mg/1ml
英文名： GPRC5C
别名： G-protein coupled receptor family C group 5 member; C; GPC5C; GPRC5C; MGC131820; PSEC0087; RAIG-3; RAIG3; Retinoic acid-induced gene 3 protein; GPC5C_HUMAN.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPRC5C
交叉反应：Human, Mouse, Rat, Pig, Sheep,
细胞定位：细胞膜
G蛋白偶联受体GPRC5C蛋白抗体产品介绍：background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPRC5C (G protein-coupled receptor, family C, group 5, member C), also known as RAIG3, is a 441 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and belongs to the G protein-coupled receptor family. Expressed at high levels in stomach, liver, prostate, kidney and pancreas, GPRC5C is thought to function as a retinoic acid-inducible GPR that may play a role in signaling events throughout the cell. GPRC5C is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR. Function: G蛋白偶联受体GPRC5C蛋白抗体This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles. Tissue Specificity: Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in G蛋白偶联受体GPRC5C蛋白抗体the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). Similarity: Belongs to the G-protein coupled receptor 3 family. Database links: Entrez Gene: 55890 Human Entrez Gene: 70355 Mouse Entrez Gene: 287805 Rat Omim: 605949 Human SwissProt: Q9NQ84 Human SwissProt: Q8K3J9 Mouse SwissProt: Q3KRC4 Rat Unigene: 446438 Human Unigene: 242413 Mouse Unigene: 3658 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体GPRC5C蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid