CD39/ENTPD3抗体
规格：1mg/1ml
英文名： CD39
别名： entpd1; ATPDase; CD 39; CD39; CD39 antigen; DKFZp686D194; DKFZp686I093; Ecto apyrase; Ecto ATP diphosphohydrolase; Ecto-apyrase; Ecto-ATP diphosphohydrolase 1; Ecto-ATPase 1; Ecto-ATPDase 1; Ectonucle
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD39/ent
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：细胞膜
CD39/ENTPD3抗体产品介绍：background: Members of the ecto-nucleoside triphosphate diphosphohydrolase (eNTPDase) protein family are glycosylated enzymes that hydrolyze nucleoside 5’-triphosphates and 5’-diphosphates in extracellcular space. The enzymatic activities of eNTPDase are dependent on cations such as magnesium and calcium. Members of this protein family differ in their affinities for triphosphates versus diphosphates as substrate material. CD39L3, also known as Ectonucleoside triphosphate diphosphohydrolase 3 or NTPDase 3, is a 529 amino acid multi-pass membrane protein that has a three-fold preference for hydrolysis of ATP over ADP. Both calcium and magnesium serve as cofactors for CD39L3’s extremely active extracellular nucleotide hydrolysis site. CD39L3 is expressed in spleen, prostate, brain and pancreas, CD39/ENTPD3抗体though moderate to low expression is observed in most tissues, with the exception of liver and peripheral blood leukocytes. Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Subunit: Homodimer; disulfide-linked (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Tissue Specificity: Expressed primarily on activatedCD39/ENTPD3抗体 lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only. Post-translational modifications: The N-terminus is blocked. Palmitoylated in the N-terminal part. Similarity: Belongs to the GDA1/CD39 NTPase family. Gene ID: 953 Database links: Entrez Gene: 953 Human Entrez Gene: 12495 Mouse Entrez Gene: 64519 Rat Omim: 601752 Human SwissProt: P49961 Human SwissProt: P55772 Mouse SwissProt: P97687 Rat Unigene: 576612 Human Unigene: 2824 Mouse Unigene: 17491 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD39/ENTPD3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid