G蛋白偶联受体GPR78蛋白抗体
规格：1mg/1ml
英文名： GPR78
别名： GPCR GPR78; G-protein coupled receptor 78; GPR78; UNQ5925/PRO19818; GPR78_HUMAN; GPCR 78.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPR78
交叉反应：Human,
细胞定位：细胞膜
G蛋白偶联受体GPR78蛋白抗体产品介绍：background: The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene.G蛋白偶联受体GPR78蛋白抗体 [provided by RefSeq, Nov 2011] Function: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: High level of expression in placenta. Expressed throughout the brain at low level. No expression G蛋白偶联受体GPR78蛋白抗体detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 27201 Database links: Entrez Gene: 27201 Human Omim: 606921 Human SwissProt: Q96P69 Human Unigene: 350588 Human Unigene: 740355 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体GPR78蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid