9号染色体开放阅读框140抗体
规格：1mg/1ml
英文名： C9orf140
别名： 2010317E24Rik; C9orf140; Chromosome 9 open reading frame 140; SAPC2_HUMAN; p42.3; Protein C9orf140; SAPCD2; Suppressor APC domain containing 2; Suppressor APC domain containing protein 2; TS/MDEP; Tum
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C9orf140
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit,
细胞定位：
9号染色体开放阅读框140抗体产品介绍：background: C9orf140 (chromosome 9 open reading frame 140), also known as TS/MDEP (tumor specificity and mitosis phase-dependent expression protein) or p42.3, is a 394 amino acid nuclear and cytoplasmic protein encoded by a gene that maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with 9号染色体开放阅读框140抗体chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed in 5-month-old fetal tissues, i9号染色体开放阅读框140抗体ncluding stomach, intestine, colon, liver, brain, lung, heart, spleen and kidney. Undetectable in non-cancerous ***** tissues. Expressed in many primary gastric carcinoma, but almost not in adjacent normal mucosa. Expressed preferentially in M and G1 phases, compared to S and G2 phases. Database links: UniProtKB/Swiss-Prot: Q86UD0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
9号染色体开放阅读框140抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid