碳酸氢钠协同转运蛋白4-A7抗体
规格：1mg/1ml
英文名： Slc4a7
别名： NBC3; NBCn1; Slc4a7; Nbc; Nbc2; Nbc3; Bicarbonate transporter; BT; NBC2; NBC3; S4A7; SBC2; SLC4A6; Sodium bicarbonate cotransporter 2; Sodium bicarbonate cotransporter 2b; Sodium bicarbonate cotranspo
分子量： 140kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat Slc4a7
交叉反应：Human, Mouse, Rat,
细胞定位：
碳酸氢钠协同转运蛋白4-A7抗体产品介绍：background: Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity. Function: Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity Subunit: Interacts with USH1C. Forms a complex with ATP6V1B1 and SLC9A3R1/EBP50. Interacts in a pH dependent-manner with CA2/carbonic anhydrase 2. Interacts with CFTR probably through SLC9A3R1/EBP50. Subcellular Location: Basolateral cell membrane; Multi-pass membrane 碳酸氢钠协同转运蛋白4-A7抗体protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells. Tissue Specificity: Expressed in aorta, ventricles, atrium, mesenteric artery, kidney, spleen, duodenum, jejunum, ileum, colon, lung, trachea, gastric fundus and pylorus, cerebrum, cerebellum, pancreas, liver, parotid gland, and epididymis. Expressed in the inner ear by cochlear outer and inner hair cells碳酸氢钠协同转运蛋白4-A7抗体 (at protein level). Highly expressed in testis and spleen. Also detected in heart, brain, lung, liver and kidney. Isoform 4 and isoform 5 are specifically expressed in kidney. Isoform 6 is specifically expressed in hippocampal neurons. Post-translational modifications: N-glycosylated. Similarity: Belongs to the anion exchanger (TC 2.A.31) family. Gene ID: 9497 Database links: Entrez Gene: 9497 Human Omim: 603353 Human SwissProt: Q9Y6M7 Human Unigene: 250072 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SLC4A7属溶质性载体家族成碳酸氢钠协同转运蛋白4-A7抗体员，是物质转运和在能量传递中起到重要作用的蛋白。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid