20号染色体开放阅读框74抗体
规格:1mg/1ml
英文名: C20orf74
别名: 250 kDa substrate of Akt; Akt substrate AS250; AS250; bA287B20.1; dJ1049G11; dJ1049G11.4; KIAA1272; p220; Ral GTPase-activating protein alpha subunit 2; Ral GTPase-activating protein subunit alpha-2;
分子量: 211kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C20orf74
交叉反应:Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
20号染色体开放阅读框74抗体产品介绍:background: AS250 is a 1,873 amino acid protein encoded by a gene which maps to human chromosome 20. Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis which are thought important for seminal production and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies20号染色体开放阅读框74抗体, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. Function: Catalytic subunit of the heterodimeric RalGAP2 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB (By similarity). Subunit: Component of 20号染色体开放阅读框74抗体the heterodimeric RalGAP2 complex with RALGAPB. Heterodimerization is required for activity (By similarity). Subcellular Location: Cytoplasm. Similarity: Contains 1 Rap-GAP domain. Database links: Entrez Gene: 57186 Human Entrez Gene: 241694 Mouse SwissProt: Q2PPJ7 Human SwissProt: A3KGS3 Mouse Unigene: 472285 Human Unigene: 222310 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
20号染色体开放阅读框74抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid