AATK细胞凋亡关联酪氨酸激酶抗体
规格:1mg/1ml
英文名: AATK
别名: AATK; AATYK; AATYK1; Apoptosis associated tyrosine kinase; Apoptosis-associated tyrosine kinase; Brain apoptosis associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5 binding pr
分子量: 151kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human AATK
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆 细胞膜
AATK细胞凋亡关联酪氨酸激酶抗体产品介绍:background: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene.AATK细胞凋亡关联酪氨酸激酶抗体 [provided by RefSeq, Jun 2011] Function: Apoptosis associated tyrosine kinase May be involved in neuronal differentiation. Subunit: Interacts with CDK5. Subcellular Location: Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, AATK细胞凋亡关联酪氨酸激酶抗体perinuclear region. Tissue Specificity: Expressed in brain, and, to a lower extent, in kidney, heart, lung and skeletal muscle. Belongs to the protein kinase superfamily. Tyr protein kinase family. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Contains 1 protein kinase domain. Gene ID: 9625 Database links: Entrez Gene: 9625 Human Omim: 605276 Human SwissProt: Q6ZMQ8 Human Unigene: 514575 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
AATK细胞凋亡关联酪氨酸激酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid