20号染色体开放阅读框117抗体
规格：1mg/1ml
英文名： C20orf117
别名： C20orf117; CT117_HUMAN; dJ132F21.1; FLJ44670; hypothetical protein LOC140710; KIAA0889; Uncharacterized protein C20orf117.
分子量： 160kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C20orf11
交叉反应：Human, Mouse, Rat, Pig,
细胞定位：
20号染色体开放阅读框117抗体产品介绍：background: Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf11720号染色体开放阅读框117抗体 gene product has been provisionally designated C20orf117 pending further characterization. Function: Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity). Subunit: The C-terminal 25 kDa form occurs as a monomer (By similarity). Subcellular Location: C-terminal 80 kDa form: Secreted (By similarity). Note=Secreted20号染色体开放阅读框117抗体 in primary hepatocyte-conditioned media (By similarity). Post-translational modifications: Proteolytically cleaved in primary hepatocytes into a C-terminal 80 kDa form (By similarity). Proteolytically cleaved into a C-terminal SOGA 25 kDa form that is detected in plasma. Similarity: Belongs to the SOGA family. Database links: UniProtKB/Swiss-Prot: O94964.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
20号染色体开放阅读框117抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid