1号染色体开放阅读框86抗体
规格：1mg/1ml
英文名： C1orf86
别名： C1orf86; CA086_HUMAN; Chromosome 1 open reading frame 86; FP7162; RP11-181G12.3; Uncharacterized protein C1orf86.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C1orf86
交叉反应：Human, Mouse, Rat,
细胞定位：
1号染色体开放阅读框86抗体产品介绍：background: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction 1号染色体开放阅读框86抗体with REV1. Subunit: Component of the Fanconi anemia (FA) complex. Interacts with FANCA; interaction is direct. Interacts with REV1. Reported to bind monoubiquitinated REV1; however it binds better to non-ubiquitinated REV1 (PubMed:22266823). Subcellular Location: Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. Similarity: Contains 1 UBZ-type zinc finger. Gene ID: 199990 Database links: Entrez Gene: 199990 Human Omim: 615183 Human 1号染色体开放阅读框86抗体SwissProt: Q6NZ36 Human Unigene: 107101 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
1号染色体开放阅读框86抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid