1号染色体开放阅读框194抗体
规格:1mg/1ml
英文名: C1orf194
别名: C1orf194; CA194_HUMAN; Chromosome 1 open reading frame 194; Hypothetical protein LOC1270032; OTTHUMP00000013446; OTTHUMP00000013448; Uncharacterized protein C1orf194.
分子量: 19kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C1orf194
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
1号染色体开放阅读框194抗体产品介绍:background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located 1号染色体开放阅读框194抗体on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma 1号染色体开放阅读框194抗体and multiple myeloma. The C1orf194 gene product has been provisionally designated C1orf194 pending further characterization. There are two isoforms of C1orf194 that are produced as a result of alternative splicing events. Gene ID: 127003 Database links: Entrez Gene: 127003 Human SwissProt: Q5T5A4 Human Unigene: 446962 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
1号染色体开放阅读框194抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid