CXCL10趋化因子10/干扰素诱导蛋白10抗体
规格:1mg/1ml
英文名: CXCL10/IP10
别名: 10 kDa interferon gamma induced protein; C7; Chemokine (C X C motif) ligand 10; Chemokine CXC motif ligand 10; Crg 2; CRG2; CXCL 10; CXCL10; Gamma IP10; gIP 10; GIP10; IFI 10; IFI10; INP 10; INP10; In
分子量: 10kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from mouse CXCL10
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
CXCL10趋化因子10/干扰素诱导蛋白10抗体产品介绍:background: Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation CXCL10趋化因子10/干扰素诱导蛋白10抗体of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Function: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Subcellular Location: Secreted. Post-translational modifications: CXCL10(1-73) is produced byCXCL10趋化因子10/干扰素诱导蛋白10抗体 proteolytic cleavage after secretion from keratinocytes. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. Gene ID: 15945 Database links: Entrez Gene: 3627 Human Entrez Gene: 15945 Mouse Entrez Gene: 245920 Rat Omim: 147310 Human SwissProt: P02778 Human SwissProt: P17515 Mouse SwissProt: P48973 Rat Unigene: 632586 Human Unigene: 877 Mouse Unigene: 10584 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CXCL10趋化因子10/干扰素诱导蛋白10抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid