FAM125A蛋白抗体
规格：1mg/1ml
英文名： FAM125A
别名： CFBP; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; F125A_HUMAN; FAM125A; Family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM125A
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞核 细胞浆
FAM125A蛋白抗体产品介绍：background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor. Subcellular Location: Cytoplasm. Nucleus. Endosome. Cytoplasm > cytoskeleton > centrosome. FAM125A蛋白抗体Late endosome membrane. Colocalizes with F-actin. Some fraction may be nuclear. Tissue Specificity: Ubiquitously expressed except in skeletal muscle. Post-translational modifications: Phosphorylated on Tyr-204 upon EGF stimulation. Phosphorylation is required for interaction with CD2AP and CIN85/SH3KBP1. Similarity: Belongs to the FAM125 family. Contains 1 MABP domain. Contains 1 UMA domain. Gene FAM125A蛋白抗体ID: 93343 Database links: Entrez Gene: 93343 Human SwissProt: Q96EY5 Human Unigene: 515243 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAM125A蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid