肿瘤转移抑制蛋白1抗体
规格:1mg/1ml
英文名: CD82
别名: 4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KA
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CD82
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位:细胞膜
肿瘤转移抑制蛋白1抗体产品介绍:background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two肿瘤转移抑制蛋白1抗体 alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. Subunit: Interacts directly with 肿瘤转移抑制蛋白1抗体IGSF8. Subcellular Location: Membrane. Tissue Specificity: Lymphoid specific. Similarity: Belongs to the tetraspanin (TM4SF) family. Gene ID: 3732 Database links: Entrez Gene: 3732 Human Entrez Gene: 12521 Mouse Entrez Gene: 83628 Rat Omim: 600623 Human SwissProt: P27701 Human SwissProt: P40237 Mouse SwissProt: O70352 Rat Unigene: 527778 Human Unigene: 4261 Mouse Unigene: 3022 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信号传导(Signaling Intermediates)
肿瘤转移抑制蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 转录调节因子 细胞表面分子 细胞类型标志物 t-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid