G蛋白偶联受体75抗体
规格:1mg/1ml
英文名: GRP75
别名: G protein-coupled receptor75; 75 kDa glucose regulated protein; 75 kDa glucose-regulated protein; CSA; Glucose Regulated Protein; Grp 75; GRP75; Heat shock 70kD protein 9; heat shock 70kDa protein 9;
分子量: 70kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GRP75
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核 细胞浆
G蛋白偶联受体75抗体产品介绍:background: This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2. Function: Implicated in the control of cell proliferation and cellular aging. May also act as a G蛋白偶联受体75抗体chaperone. Subunit: Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Subcellular Location: Mitochondrion. Nucleus, nucleolus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: G蛋白偶联受体75抗体Belongs to the heat shock protein 70 family. Gene ID: 3313 Database links: Entrez Gene: 3313 Human Entrez Gene: 15526 Mouse Entrez Gene: 291671 Rat Omim: 600548 Human SwissProt: P38646 Human SwissProt: P38647 Mouse SwissProt: P48721 Rat Unigene: 184233 Human Unigene: 209419 Mouse Unigene: 7535 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信号传导(Signaling Intermediates) 葡萄糖调节蛋白75
G蛋白偶联受体75抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 细胞膜受体 转运蛋白 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid