FAAP24蛋白抗体
规格：1mg/1ml
英文名： FAAP24
别名： C19ORF40; C19orf40 chromosome 19 open reading frame 40; FAAP24; Fanconi anemia-associated protein 24 kDa; Fanconi anemia-associated protein of 24 kDa; FAP24_HUMAN; MGC32020.
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAAP24
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
FAAP24蛋白抗体产品介绍：background: FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008] Function: FAAP24 was identified as a protein that interacts with FANCM as part of the core Fanconi Anemia complex. It is homologous to the XPF family of FAAP24蛋白抗体endonucleases. FAAP24 is required for normal levels of FANCD2 ubiquitination after DNA damage. Knockdown of FAAP24 leads to chromosomal instability. Subunit: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCGFAAP24蛋白抗体, FANCL/PHF9, FANCM and FAAP24. Interacts with FANCM. Subcellular Location: Nuclear Gene ID: 91442 Database links: Entrez Gene: 91442 Human Omim: 610884 Human SwissProt: Q9BTP7 Human Unigene: 579899 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAAP24蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid