EXOC8蛋白抗体
规格：1mg/1ml
英文名： EXOC8
别名： EXO84; Exo84p; exoc8; EXOC8_HUMAN; Exocyst complex 84 kDa subunit; Exocyst complex component 8; SEC84.
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EXOC8
交叉反应：Human, Mouse,
细胞定位：细胞浆
EXOC8蛋白抗体产品介绍：background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis.EXOC8蛋白抗体 Exo84 (Exocyst complex 84 kDa subunit), also known as Exocyst complex component 8, is a 725 amino acid protein that is one of eight protein subunits composing the mammalian exocyst complex. Both Exo84 and Sec5 are effector targets for active Ral GTPases, which are responsible for regulating exocyst complex activities. Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subcellular Location: Cytoplasm. Cell projection > growth cone. Redistributes to growing neurites and growth EXOC8蛋白抗体cones during cell differentiation (By similarity). Binds lipids with phosphatidylinositol-3,4,5-trisphosphate groups. Similarity: Belongs to the EXO84 family. Contains 1 PH domain. Database links: Entrez Gene: 149371 Human Entrez Gene: 102058 Mouse Omim: 615283 Human SwissProt: Q8IYI6 Human SwissProt: Q6PGF7 Mouse Unigene: 356198 Human Unigene: 347360 Mouse Unigene: 392449 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EXOC8蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid