内质网氨基肽酶2抗体
规格：1mg/1ml
英文名： ERAP2
别名： Endoplasmic reticulum aminopeptidase 2; L RAP; MUT7_HUMAN; Leukocyte derived arginine aminopeptidase; LRAP.
分子量： 97kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ERAP2
交叉反应：Human,
细胞定位：
内质网氨基肽酶2抗体产品介绍：background: Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II内质网氨基肽酶2抗体 (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).[supplied by OMIM, Mar 2008] Function: ERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase内质网氨基肽酶2抗体 II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Similarity: Belongs to the mut-7 family. Contains 1 3'-5' exonuclease domain. Gene ID: 64167 Database links: Entrez Gene: 64167 Human Omim: 609497 Human SwissProt: Q6P179 Human Unigene: 482910 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内质网氨基肽酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid