ESSPL蛋白抗体
规格：1mg/1ml
英文名： ESSPL
别名： Epidermis specific serine protease like protein; Epidermis-specific serine protease-like protein; Gm1019; Protease serine 48; PRS48_HUMAN; PRSS48; Serine protease 48.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ESSPL
交叉反应：Human,
细胞定位：细胞浆
ESSPL蛋白抗体产品介绍：background: ESPNL is a 1,005 amino acid protein that contains nine ANK repeats and exists as three alternatively spliced isoforms. The gene encoding ESPNL maps to human chromosome 2q37.3 and mouse chromosome 1 D. Chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, ESSPL蛋白抗体is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder known as Alstrom syndrome is due to mutations in the ALMS1 gene. Interestingly,ESSPL蛋白抗体 chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. Subcellular Location: Secreted. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Gene ID: 345062 Database links: Entrez Gene: 345062 Human SwissProt: Q7RTY5 Human Unigene: 651266 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ESSPL蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid