ESPNL蛋白抗体
规格:1mg/1ml
英文名: ESPNL
别名: Espin-like; Espin-like protein; Espnl; ESPNL_HUMAN.
分子量: 108kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ESPNL
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig,
细胞定位:
ESPNL蛋白抗体产品介绍:background: ESPNL is a 1,005 amino acid protein that contains nine ANK repeats and exists as three alternatively spliced isoforms. The gene encoding ESPNL maps to human chromosome 2q37.3 and mouse chromosome 1 D. Chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity,ESPNL蛋白抗体 is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder known as Alstrom syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human ESPNL蛋白抗体chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. Similarity: Contains 9 ANK repeats. Gene ID: 339768 Database links: Entrez Gene: 339768 Human Entrez Gene: 227357 Mouse SwissProt: Q6ZVH7 Human SwissProt: Q3UYR4 Mouse Unigene: 127724 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ESPNL蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转运蛋白 新陈代谢 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid