ENTPD8蛋白抗体
规格：1mg/1ml
英文名： ENTPD8
别名： E NTPDase 8; ENTP8_HUMAN; EC 3.6.1.5; ecto-ATP-diphosphohydrolase; Ectonucleoside triphosphate diphosphohydrolase 8; GLSR2492; iver ecto ATP diphosphohydrolase; NTPDase 8; nucleoside triphosphate diph
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ENTPD8
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
ENTPD8蛋白抗体产品介绍：background: Members of the ecto-nucleoside triphosphate diphosphohydrolase (eNTPDase) protein family are glycosylated enzymes that hydrolyze nucleoside 5’-triphosphates and 5’-diphosphates in extracellcular space. The enzymatic activities of eNTPDase are dependent on cations such as magnesium and calcium. Members of this protein family differ in their affinities for triphosphates versus diphosphates as substrate material. NTPDase8, also known as ENTPD8 (ectonucleoside triphosphate diphosphohydrolase 8) or E-NTPDase 8, is a 495 amino acid multi-pass membrane protein belonging to the GDA1/CD39 NTPase family. As a canalicular ectonucleoside NTPDaseENTPD8蛋白抗体, NTPDase8 is involved in hepatic NTPDase activity and helps concentrate extracellular nucleotides. NTPDase8 binds calcium as a cofactor, becomes glycosylated following translation and exists as two alternatively spliced isoforms. Function: ENTPD8 is a canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP,ENTPD8蛋白抗体 but not toward AMP. There are two different isoforms. Subcellular Location: Cell membrane; Multi-pass membrane protein. Post-translational modifications: N-glycosylated. Similarity: Belongs to the GDA1/CD39 NTPase family. Gene ID: 377841 Database links: Entrez Gene: 377841 Human SwissProt: Q5MY95 Human Unigene: 512562 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ENTPD8蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid