ENTPD4蛋白抗体
规格：1mg/1ml
英文名： ENTPD4
别名： Apyrase lysosomal; Ectonucleoside triphosphate diphosphohydrolase 4; ENTPD 4; Golgi luminal UDPase; Guanosine diphosphatase like protein; KIAA0392; LALP70; ENTP4_HUMAN; LAP70; LYSAL1; Lysosomal apyras
分子量： 70kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ENTPD4
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：
ENTPD4蛋白抗体产品介绍：background: This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq,ENTPD4蛋白抗体 Sep 2011] Function: ENTPD4 (Ectonucleoside triphosphate diphosphohydrolase 4) preferentially hydrolyzes nucleoside 5'-diphosphates. Nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP. AMP, ADP, ATP and UMP are not substrates. There are two named isoforms. The preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP. Subcellular Location: Golgi apparatus membrane; Multi-pass membrane protein.ENTPD4蛋白抗体 Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note: Localizes in the Golgi and autophagic vacuoles/lysosomes. Tissue Specificity: Ubiquitous. Highest expression in testis and lowest in bladder. Similarity: Belongs to the GDA1/CD39 NTPase family. Gene ID: 9583 Database links: Entrez Gene: 9583 Human Entrez Gene: 67464 Mouse Entrez Gene: 361063 Rat Omim: 607577 Human SwissProt: Q9Y227 Human SwissProt: Q9DBT4 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ENTPD4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid