ENOX1蛋白抗体
规格:1mg/1ml
英文名: ENOX1
别名: bA64J21.1; Candidate growth related and time keeping constitutive hydroquinone [NADH] oxidase; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase; cCNOX; Cell prolifera
分子量: 73kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ENOX1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆 细胞膜
ENOX1蛋白抗体产品介绍:background: This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian ENOX1蛋白抗体cellular biological clock. Subcellular Location: Cell membrane. Secreted; extracellular space. Extracellular and plasma membrane-associated. Tissue Specificity: Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serumENOX1蛋白抗体 of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Similarity: Belongs to the ENOX family. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 10495 Database links: Entrez Gene: 10495 Human Entrez Gene: 55068 Human Entrez Gene: 209224 Mouse Entrez Gene: 239188 Mouse Entrez Gene: 306038 Rat Omim: 610914 Human SwissProt: Q16206 Human SwissProt: Q8TC92 Human SwissProt: Q8BHR2 Mouse SwissProt: Q8R0Z2 Mouse Unigene: 128258 Human Unigene: 171458 Human Unigene: 327730 Mouse Unigene: 441158 Mouse Unigene: 490096 Mouse Unigene: 212211 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ENOX1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid