白血病抑制因子受体抗体
规格：1mg/1ml
英文名： LIFR
别名： CD 118; leukemia inhibitory factor receptor; SWS; SJS2; STWS; CD118; LIF-R; FLJ98106; FLJ99923; LIFR; Leukemia inhibitory factor receptor alpha; LIF R; LIF receptor; LIFR_RAT.
分子量： 117kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from the middle of
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞膜
白血病抑制因子受体抗体产品介绍：background: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the ***** and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type白血病抑制因子受体抗体 of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. Function: Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity). Subunit: "Heterodimer composed of LIFR and IL6ST. The heterodimer白血病抑制因子受体抗体 formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 6 fibronectin type-III domains. Gene ID: 81680 Database links: Entrez Gene: 3977 Human Entrez Gene: 16880 Mouse Entrez Gene: 81680 Rat Omim: 151443 Human SwissProt: P42702 Human SwissProt: P42703 Mouse SwissProt: O70535 Rat Unigene: 133421 Human Unigene: 149720 Mouse Unigene: 14529 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白血病抑制因子受体抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid