EMR4蛋白抗体
规格：1mg/1ml
英文名： EMR4
别名： EGF like module containing mucin like hormone receptor like 4; EGF TM7 receptor EMR4; EMR4P; EMR4_HUMAN; FIRE; G protein coupled receptor 127; G protein coupled receptor PGR16; GPR127; PGR16; Putative
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EMR4
交叉反应：Human, Mouse, Rat, Cow, Sheep,
细胞定位：细胞膜
EMR4蛋白抗体产品介绍：background: This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble ratherEMR4蛋白抗体 than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008] Function: EMR4 could mediate the cellular interaction between myeloid cells and B-cells. Subunit: Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit)EMR4蛋白抗体(By similarity). Subcellular Location: Cell Membrane; multi pass membrane protein Post-translational modifications: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity). Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 2 EGF-like domains. Contains 1 GPS domain. Gene ID: 326342 Database links: Entrez Gene: 326342 Human Omim: 612305 Human SwissProt: Q86SQ3 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EMR4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 细胞粘附分子 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid