弹性蛋白微原纤维界面因子2抗体
规格：1mg/1ml
英文名： EMILIN2
别名： Elastin microfibril interface-located protein 2; Elastin microfibril interfacer 2; EMIL2_HUMAN; EMILIN-2; EMILIN2; extracellular glycoprotein EMILIN-2; FOAP-10; Protein FOAP-10.
分子量： 112kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EMILIN2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
弹性蛋白微原纤维界面因子2抗体产品介绍：background: EMILINs (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine rich EMI domain and a conserved C-terminal gC1q-like domain. EMILIN-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. EMILIN-2 is larger than EMILIN-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as EMILIN-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as EMILIN-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for弹性蛋白微原纤维界面因子2抗体 platelet factor V. EMILIN-5 is encoded by the EMILIN3 gene and is sometimes referred to as EMILIN-3. It contains the N-terminal cysteine rich EMI domain but lacks the C-terminal gC1q-like domain. EMILIN-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development. Function: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Subcellular弹性蛋白微原纤维界面因子2抗体 Location: Secreted > extracellular space > extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils. Tissue Specificity: Highest levels are present in fetal heart and ***** lung. Intermediate levels in peripheral leukocytes, placenta, and spinal cord and low expression in fetal brain, spleen, thymus, and lung and in ***** heart, aorta, testis, bone marrow, small intestine, thymus, lymph node, and appendix. Similarity: Contains 1 C1q domain. Contains 1 collagen-like domain. Contains 1 EMI domain. Gene ID: 84034 Database links: Entrez Gene: 84034 Human SwissProt: Q9BXX0 Human Unigene: 532815 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
弹性蛋白微原纤维界面因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导 糖蛋白 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid