血清反应因子辅助蛋白SAP2抗体
规格:1mg/1ml
英文名: ELK3
别名: ELK3; ELK3, ETS domain protein (SRF accessory protein 2); ELK3_HUMAN; ERP; ETS domain protein; ETS domain-containing protein Elk-3; ETS related protein ERP; ETS related protein NET; ETS-related protei
分子量: 44kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ELK3
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位:细胞核
血清反应因子辅助蛋白SAP2抗体产品介绍:background: The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by RefSeq, Jul 2008] Function: May be a 血清反应因子辅助蛋白SAP2抗体negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. Subunit: 血清反应因子辅助蛋白SAP2抗体Interacts with CTBP1. Subcellular Location: Nucleus. Similarity: Belongs to the ETS family. Contains 1 ETS DNA-binding domain. Gene ID: 2004 Database links: Entrez Gene: 2004 Human Entrez Gene: 417919 Chicken Entrez Gene: 541125 Cow Entrez Gene: 482613 Dog Entrez Gene: 13713 Mouse Entrez Gene: 362871 Rat Omim: 600247 Human SwissProt: P41970 Human SwissProt: P41971 Mouse Unigene: 46523 Human Unigene: 4454 Mouse Unigene: 196088 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血清反应因子辅助蛋白SAP2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid