ELF2蛋白抗体
规格:1mg/1ml
英文名: ELF2
别名: E74 like factor 2; E74 like factor 2 ets domain transcription factor; ELF 2; Ets related factor; EU 32; EU32; ELF2_HUMAN; HGNC:3317; NERF 1A; NERF 1a b; NERF 1B; NERF 2; NERF; NERF1A; NERF1a b; NERF2;
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ELF2
交叉反应:Human, Mouse, Rat, Dog, Horse, Sheep,
细胞定位:细胞核
ELF2蛋白抗体产品介绍:background: The ELF2 gene encodes a protein that physically interacts with AML1 and mediates opposing effects on AML1 mediated transcription of the B cell specific blk gene. Function: Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. Isoform 2 may function in repression of RUNX1-mediatedELF2蛋白抗体transactivation. Subunit: Interacts with the LIM domains of LMO2 (By similarity). Interacts via its N-terminal region with RUNX1. Subcellular Location: Nuclear Tissue Specificity: Expressed in all fetal and ***** tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among ***** tissues, highest levels of expression detected in heart, placenta, ELF2蛋白抗体lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes. Similarity: Belongs to the ETS family. Gene ID: 69257 Database links: Entrez Gene: 69257 Mouse SwissProt: Q15723 Human SwissProt: P52800 Mouse SwissProt: Q9JHC9 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ELF2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid