RNase Z1蛋白抗体
规格：1mg/1ml
英文名： ELAC1
别名： D29; Deleted in Ma29; ELAC 1; ElaC homolog 1 (E. coli); ElaC homolog 1; ElaC homolog protein 1; ELAC1; Ribonuclease Z 1; RNase Z 1; RNZ1_HUMAN; tRNA 3 endonuclease 1; tRNA 3' processing endoribonuclea
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ELAC1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
RNase Z1蛋白抗体产品介绍：background: ELAC1 is a 363 amino acid nuclear protein that belongs to the RNase Z family of RNA-processing enzymes. Expressed throughout the body with highest expression in lung, brain, placenta, heart, liver, kidney and pancreas, RNase Z1 is a zinc phosphodiesterase that plays a role in tRNA maturation by removing 3'-trailer segments from precursor tRNA. In addition, RNase Z has a variety of other zinc-dependent RNA processing activities, including generation of 3' termini on tRNA, endonucleolytic cleavage of RNA and removal ofRNase Z1蛋白抗体 extra 3' nucleotides from unprocessed tRNA. Defects in the gene encoding RNase Z1 may be involved in the pathogenesis of prostate cancer, suggesting a possible role for RNase Z1 in carcinogenesis. Function: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Subcellular Location: RNase Z1蛋白抗体Nucleus. Tissue Specificity: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the RNase Z family. Gene ID: 55520 Database links: Entrez Gene: 55520 Human Entrez Gene: 532568 Cow Entrez Gene: 114615 Mouse Omim: 608079 Human SwissProt: Q29RY4 Cow SwissProt: Q9H777 Human SwissProt: Q8VEB6 Mouse Unigene: 657360 Human Unigene: 50642 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNase Z1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 神经生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid