eIF5A2蛋白抗体
规格：1mg/1ml
英文名： eIF5A2
别名： 9630038B20; eIF 5A 2; eIF 5A2; eIF-4D; eIF-5A-2; eIF-5A2; EIF5A 2; EIF5A2; eIF5AII; Eukaryotic initiation factor 5A isoform 2; Eukaryotic translation initiation factor 5A-2; Eukaryotic translation ini
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human eIF5A2
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞核 细胞浆
eIF5A2蛋白抗体产品介绍：background: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Subcellular Location: Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. HypusineeIF5A2蛋白抗体 modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. Tissue Specificity: Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells. Post-translational modifications: eIF-5A seemseIF5A2蛋白抗体 to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine). Similarity: Belongs to the eIF-5A family. Gene ID: 56648 Database links: Entrez Gene: 56648 Human Entrez Gene: 208691 Mouse Entrez Gene: 310261 Rat Omim: 605782 Human SwissProt: Q9GZV4 Human SwissProt: Q8BGY2 Mouse Unigene: 164144 Human Unigene: 193670 Mouse Unigene: 47334 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
eIF5A2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid