EIF2B2蛋白抗体
规格：1mg/1ml
英文名： EIF2B2
别名： EI2BB_HUMAN; EIF 2Bbeta; EIF-2Bbeta; EIF2B; EIF2B GDP GTP exchange factor subunit beta; EIF2B2; EIF2B2; ; EIF2BB; Eukaryotic translation initiation factor 2B; Eukaryotic translation initiation factor
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EIF2B2
交叉反应：Human, Mouse, Rat, Cow, Rabbit,
细胞定位：
EIF2B2蛋白抗体产品介绍：background: This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011] Function: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Subunit: Complex of five different subunits; alpha, beta, gamma, delta and epsilon. DISEASE: Leukodystrophy with vanishing white matter (VWM) [MIM:603896]: A leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease isEIF2B2蛋白抗体chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident EIF2B2蛋白抗体until adolescence or *****hood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. Gene ID: 8892 Database links: Entrez Gene: 8892 Human Entrez Gene: 513958 Cow Entrez Gene: 217715 Mouse Entrez Gene: 84005 Rat Entrez Gene: 405839 Zebrafish Omim: 606454 Human SwissProt: Q5E9B4 Cow SwissProt: P49770 Human SwissProt: Q99LD9 Mouse SwissProt: Q28690 Rabbit SwissProt: Q62818 Rat Unigene: 409137 Human Unigene: 29041 Mouse Unigene: 5910 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EIF2B2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid