硒特异延伸因子/SELB抗体
规格：1mg/1ml
英文名： EEFSEC
别名： EFSEC; SELB_HUMAN； Elongation factor for selenoprotein translation; Elongation factor sec; Eukaryotic elongation factor, selenocysteine tRNA specific; SELB; Selenocysteine specific elongation factor.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EEFSEC
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞核 细胞浆
硒特异延伸因子/SELB抗体产品介绍：background: EEFSEC is a 596 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the GTP-binding elongation factor family. Functioning as a translation factor, SELB binds GTP and GDP and is necessary for the incorporation of selenocysteine into target proteins. The gene encoding SELB maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B硒特异延伸因子/SELB抗体. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: EEFSEC is a translation factor necessary 硒特异延伸因子/SELB抗体for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. Subcellular Location: Cytoplasmic and Nuclear. Similarity: Belongs to the GTP-binding elongation factor family. SelB subfamily. Gene ID: 60678 Database links: Entrez Gene: 60678 Human Entrez Gene: 65967 Mouse Omim: 607695 Human SwissProt: P57772 Human SwissProt: Q9JHW4 Mouse Unigene: 477498 Human Unigene: 333237 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒特异延伸因子/SELB抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid