EDC3蛋白抗体
规格：1mg/1ml
英文名： EDC3
别名： EDC 3; edc3; EDC3_HUMAN; enhancer of mRNA decapping 3 homolog (S. cerevisiae); Enhancer of mRNA decapping 3 homolog; Enhancer of mRNA decapping 3, S. cerevisiae, homolog of; Enhancer of mRNA decapping
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EDC3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞浆
EDC3蛋白抗体产品介绍：background: EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008] Edc3, enhancer of mRNA-decapping protein 3, is a 508 amino acid protein that maps to human gene EDC3. Edc3 is a member of the EDC3 family and contains one YjeF N-terminal domain. Edc3 is localized to the cytoplasm and is found primarily in the processing bodies (PBs) of the cell. Evidence indicates Edc3 also interacts with TTP (zinc finger protein 36), a candidate gene for obesity-related metabolic complications. Function: Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis. SubcellularEDC3蛋白抗体 Location: Cytoplasm; P-body. Processing bodies. Tissue Specificity: Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. Similarity: Belongs to the EDC3 family. Contains 1 DFDF domain. Contains 1 YjeF N-terminal domain. Gene ID: 80153 Database links: Entrez EDC3蛋白抗体Gene: 80153 Human Entrez Gene: 453743 Chimpanzee Entrez Gene: 101128321 Gorilla Entrez Gene: 353190 Mouse Entrez Gene: 100171859 Orangutan Omim: 609842 Human SwissProt: Q96F86 Human SwissProt: Q8K2D3 Mouse SwissProt: Q5RDU9 Orangutan Unigene: 682454 Human Unigene: 96852 Human Unigene: 268104 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EDC3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid