ECO1蛋白抗体
规格：1mg/1ml
英文名： ECO1
别名： A930014I12Rik; CTF; CTF7 homolog 1; CTF7, S. cerevisiae, homolog of, 1; ECO1; ECO1 homolog 1; ECO1, S. cerevisiae, homolog of, 1; EFO1; EFO1p; ESCO1; ESCO1_HUMAN; ESO1; ESO1 homolog 1; ESO1, S. pombe,
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ECO1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
ECO1蛋白抗体产品介绍：background: EFO1 is responsible for coupling cohesion and DNA replication processes thereby ensuring proper pairing of sister chromatids. EFO1 is phosphorylated during mitosis and this may act to regulate EFO1 activity. Due to alternative splicing events, three EFO1 isoforms exist. Function: Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, theECO1蛋白抗体 deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3. Subcellular Location: Nucleus. Chromosome. Nuclear at interphase, associated with chromosomes during mitosis. Tissue Specificity:ECO1蛋白抗体 Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle. Post-translational modifications: Phosphorylated during mitosis. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the acetyltransferase family. GCN5 subfamily. Gene ID: 114799 Database links: Entrez Gene: 114799 Human Entrez Gene: 77805 Mouse Omim: 609674 Human SwissProt: Q5FWF5 Human SwissProt: Q69Z69 Mouse Unigene: 464733 Human Unigene: 210996 Mouse Unigene: 450684 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ECO1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid