胞质动力蛋白轻链抗体2A抗体
规格：1mg/1ml
英文名： DYNLRB1
别名： BITH; bithoraxoid like protein; BLP; cytoplasmic dynein light chain 2A; DNCL2A; DNLC2A; dynein associated protein HKM23; dynein associated protein Km23; Dynein light chain 2A, cytoplasmic; dynein, cyt
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DYNLRB1
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：细胞浆
胞质动力蛋白轻链抗体2A抗体产品介绍：background: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been胞质动力蛋白轻链抗体2A抗体 defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013] Function: DYNLRB1 is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Subcellular Location: 胞质动力蛋白轻链抗体2A抗体Cytoplasmic Tissue Specificity: High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. Similarity: Belongs to the GAMAD family. Gene ID: 83658 Database links: Entrez Gene: 83658 Human Omim: 607167 Human SwissProt: Q9NP97 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞质动力蛋白轻链抗体2A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid