双特异性磷酸酶抗体9抗体
规格:1mg/1ml
英文名: DUSP9
别名: Dual specificity phosphatase 9; Dual specificity protein phosphatase 9; DUS9_HUMAN; DUSP9; MAP kinase phosphatase 4; Mitogen activated protein kinase phosphatase 4; Mitogen-activated protein kinase ph
分子量: 42kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DUSP9
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位:细胞浆
双特异性磷酸酶抗体9抗体产品介绍:background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their双特异性磷酸酶抗体9抗体 expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008] Function: Inactivates MAP kinases. Has a specificity for the ERK family. Subcellular Location: Cytoplasm. Similarity: Belongs to the protein-tyrosine双特异性磷酸酶抗体9抗体 phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain. Gene ID: 1852 Database links: Entrez Gene: 1852 Human Entrez Gene: 614306 Cow Entrez Gene: 75590 Mouse Entrez Gene: 293847 Rat Omim: 300134 Human SwissProt: Q99956 Human Unigene: 144879 Human Unigene: 16479 Mouse Unigene: 100548 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双特异性磷酸酶抗体9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid